Scientific Publications
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Optimization of Alcohol Dehydrogenase for Industrial Scale Oxidation of Lactols
Authors: Sebastian Bartsch, Jan Brummund, Sabrina Köpke, Harrie Straatman, Andreas Vogel, Martin Schürmann
published in: Biotechnology Journal, Sep 2020, Link: read the article -
Regioselective biocatalytic self-sufficient Tishchenko-type reaction via formal intramolecular hydride transfer.
Authors: Erika Tassano, Kemal Merusic, Isa Buljubasic, Olivia Laggner, Tamara Reiter, Andreas Vogel and Mélanie Hall
published in Chem. Commun., 2020, Link: read the article -
Enzyme Development Technologies.
Author: Dr. Andreas Vogel
published in "Industrial Enzyme Application", 2018, by Andreas Vogel and Oliver May, Wiley‐VCH Verlag GmbH & Co. KGaA
Link: read the paper -
Enzymatic Process for the Synthesis of Cellobiose.
Authors: Birgit Brucher and Thomas Häßler,
published in: "Industrial Enzyme Application", 2018, by Andreas Vogel and Oliver May, Wiley‐VCH Verlag GmbH & Co. KGaA
Link: read the paper -
Emerging Field - Synthesis of Complex Carbohydrates. Case Study on HMOs.
Authors: Dr. Dora Molnar-Gabor, Dr. Markus J. Hederos, Dr. Sebastian Bartsch, Dr. Andreas Vogel
published in "Industrial Enzyme Application", 2018, by Andreas Vogel and Oliver May, Wiley‐VCH Verlag GmbH & Co. KGaA
Link: read the paper -
Three in One: Temperature, Solvent and Catalytic Stability by Engineering the Cofactor-Binding Element of Amine Transaminase.
Authors:Dr. Tim Börner, Dr. Sebastian Rämisch, Dr. Sebastian Bartsch, Dr. Andreas Vogel, Prof. Patrick Adlercreutz, Assoc. Prof. Carl Grey
pubslished in: ChemBioChem, 2017, 18(15). 1482–1486.
Link: read the article -
Cost-efficient entrapment of β-glucosidase in nanoscale latex and silicone polymeric thin films for use as stable biocatalysts.
Authors: Muhammad Rizwan Javed, Andreas Buthe, Muhammad Hamid Rashid, Ping Wang
published in: Food Chemistry 2016, 190, 1078-1085. -
Improving thermal stability of thermophilic L-threonine aldolase from Thermotoga maritima. J. Biotechnol. 2015, 199, 69-76.
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ChemCatChem Selective Enzymatic Synthesis of the Grapefruit Flavor (+)-Nootkatone 2015, 601-604.
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Immobilisation of w-Transaminase for Industrial Application: Screening and Characterisation of Commercial Ready to Use Enzyme Carriers. Journal of Molecular Catalysis B: Enzymatic 2015, 117, 54-61.
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Economic Considerations for Selecting an Amine Donor in Biocatalytic Transamination. Org. Process Res. Dev. 2015.
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Enantioselective Enzymatic Synthesis of the a-Hydroxy Ketone (R)-Acetoin From Meso-2,3-Butanediol. Journal of Molecular Catalysis B: Enzymatic 2014, 103, 61-66.
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Activity-Based Profiling of a Physiologic Aglycone Library Reveals Sugar Acceptor Promiscuity of Family 1 UDP-Glucosyltransferases From Grape. Plant Physiol 2014, 166, 23-39.
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UDP-Glucose:Monoterpenol Glucosyltransferase Adds to the Chemical Diversity of the Grapevine Metabolome. Plant Physiol 2014, 165, 561-581.
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Converting Aspartase into a b-Amino Acid Lyase by Cluster Screening. ChemCatChem 2014, 6, 965-968.
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Addition of Ammonia and Amines to C=C Bonds, in Science of Synthesis – Biocatalysis in Organic Synthesis 2, Georg Thieme Verlag KG, Stuttgart, 2014, 291-312
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Enzyme-enabled responsive surfaces for anti-contamination materials. Biotechnology and Bioengineering 2013, 110(6), 1805-1810.
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Poly(ethylene glycol) Conjugated Enzyme with Enhanced Hydrophobic Compatibility for Self-Cleaning Coatings. ACS Applied Materials & Interfaces 2012, 4(11), 5981-5987.
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Enantioselective Oxidation of Aldehydes Catalyzed by Alcohol Dehydrogenase. Angew. Chem. Int. Ed Engl. 2012, 51, 9914-9917.
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Transaminases for the Synthesis of Enantiopure Beta-Amino Acids. AMB. Express 2012, 2, 11.
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Mechanism-Inspired Engineering of Phenylalanine Aminomutase for Enhanced Beta-Regioselective Asymmetric Amination of Cinnamates. Angew. Chem. Int. Ed Engl. 2012, 51, 482-486.
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Nanoporous silica glass for the immobilization of interactive enzyme systems. Methods in Molecular Biology 2011, 679 (Enzyme Stabilization and Immobilization), 37-48.
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Protein engineering: improving on nature's enzymes. Chemistry & Industry 2011, 5, 21-23.
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Organic-soluble enzyme nano-complexes formed by ion-pairing with surfactants. Methods in Molecular Biology 2011, 743 (Nanoscale Biocatalysis), 51-63.
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Multi-Enzymatic Cascade Reactions: Overview and Perspectives. Adv. Synth. Catal. 2011, 535, 2239-2262.
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Changing the substrate specificity of P450cam towards diphenylmethane by semi-rational enzyme engineering. Protein Eng Des Sel. 2011, 24, 439-446.
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Entrapment of Enzymes in Nanoporous Sol-Gels. Methods Mol. Biol. 2011, 743, 223-237.
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Cloning and Functional Expression of a Nitrile Hydratase (NHase) From Rhodococcus Equi TG328-2 in Escherichia Coli, Its Purification and Biochemical Characterisation. Appl Microbiol Biotechnol 2010, 85, 1417-1425.
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The Alpha/Beta-Hydrolase Fold 3DM Database (ABHDB) As a Tool for Protein Engineering. Chembiochem. 2010, 11, 1635-1643.
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Encapsulation of Synthetically Valuable Biocatalysts into Polyelectrolyte Multilayer Systems. Langmuir 2009, 25, 618-623.
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Highly efficient one pot dynamic kinetic resolution of benzoins with entrapped Pseudomonas stutzeri lipase. Journal of Molecular Catalysis B: Enzymatic 2008, 52-53, 133-139.
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Lipase-catalysed synthesis of ester oils from biodiesel by-products. Biocatalysis and Biotransformation 2008, 26, 220-227.
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High cell density cultivation of recombinant yeasts and bacteria under non-pressurized and pressurized conditions in stirred tank bioreactors. J. Biotechnol. 2007, 132, 167-179
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L-Lysine - Coupling of reaction and cost model for process optimization, in Development of Sustainable Bioprocesses: Modelling and Assessment, Wiley, New York, 2006
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Molecular Basis of Substrate Recognition in D-3-Hydroxybutyrate Dehydrogenase From Pseudomonas Putida. Chembiochem. 2006, 7, 1410-1418.
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Maltose and Maltodextrin Utilization by Bacillus Subtilis. J. Bacteriol. 2006, 188, 3911-3922.
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Iterative Saturation Mutagenesis on the Basis of B Factors as a Strategy for Increasing Protein Thermostability. Angew.Chem Int.Ed Engl. 2006, 45, 7745-7751.
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Expanding the Substrate Scope of Enzymes: Combining Mutations Obtained by CASTing. Chemistry 2006, 12, 6031-6038.
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Generation of lipase-containing static emulsions in silicone spheres for synthesis in organic media. Journal of Molecular Catalysis B: Enzymatic 2005, 35, 93-99.
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Expanding the Range of Substrate Acceptance of Enzymes: Combinatorial Active-Site Saturation Test. Angew. Chem Int. Ed Engl. 2005, 44, 4192-4196.
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Volsurf computational method applied to the prediction of stability of thermostable enzymes. Biocatalysis and Biotransformation 2005, 23, 307-314.
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Addressing the Challenge of Changing the Specificity of RNase T1 With Rational and Evolutionary Approaches. Chembiochem. 2004, 5, 200-205.
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RNase T1 Variant RV Cleaves Single-Stranded RNA After Purines Due to Specific Recognition by the Asn46 Side Chain Amide. Biochemistry 2004, 43, 2854-2862.