NuCLEANase® food grade

The most versatile and efficient nuclease on the market 

NuCLEANase® is a highly active nuclease from Serratia marcescens produced in a patented process based on a GRAS strain Bacillus sp. NuCLEANase degrades all forms of DNA and RNA into smaller nucleotides of about 5-8 base pairs.


Areas of application

NuCLEANase® enables the efficient removal of residual host DNA in food and feed enzymes as well as other fermentation products, such as alternative proteins and food additives, to ensure compliance with the regulatory  requirements. The reduced nucleic acid concentrations and the resulting lower viscosity also improve process efficiency. In addition, NuCLEANase increases the bioavailability of nucleotides in animal feed based on yeast extracts and “single cell protein”, which in turn improve the growth rates and immune function of animals.
In the production of phages, NuCLEANase can also reduce the concentration of nucleic acids after cell lysis, thereby increasing downstream process efficiency.


  • Removes all types of DNA and RNA
  • Cost-effective solution for degredation of nucleic acids
  • Available in bulk quantities
  • Highly active over a wide range of application conditions
  • Production processes free of antibiotics and raw materials of animal origin
  • Kosher and halal certified

Learn more about NuCLEAnase® food grade! 

More information about the product, free samples and prices can be found here:

NuCLEANase® food grade is a registered trademark of c-LEcta GmbH in Germany, the European Union, United States of America, United Kingdom, China, India.