Product Description

DENARASE® is a genetically engineered endonuclease from Serratia marcescens being able to cleave all forms of DNA and RNA very efficiently. It is commonly used in biotechnology for the quantitative removal of nucleic acids and for viscosity reduction. In the pharmaceutical industry, the endonuclease is often used to remove excess of nucleic acids in production processes of biopharmaceuticals and vaccines.

c-LEcta has developed a patent-protected production technology for this enzyme based on the recombinant expression in a Bacillus sp. production host. The production process combines high product yields with the advantages of an endotoxin-free production strain. DENARASE® has a purity of ≥ 99 % and is manufactured in full compliance with GMP requirements using only raw materials of non-animal origin and without the use of antibiotics.

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DENARASE® is a registered trademark of c-LEcta GmbH in the European Union (EU), United States of America (USA), United Kingdom (UK), China (CN), India (IN), South-Korea (KR) and Japan (JP).


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