Product Description

DENARASE® is a genetically engineered endonuclease from Serratia marcescens being able to cleave all forms of DNA and RNA very efficiently. It is commonly used in biotechnology for the quantitative removal of nucleic acids and for viscosity reduction. In the pharmaceutical industry, the endonuclease is often used to remove excess of nucleic acids in production processes of biopharmaceuticals and vaccines.

c-LEcta has developed a patent-protected production technology for this enzyme based on the recombinant expression in a Bacillus sp. production host. The production process combines high product yields with the advantages of an endotoxin-free production strain. DENARASE® has a purity of ≥ 99 % and is manufactured in full compliance with GMP requirements using only raw materials of non-animal origin and without the use of antibiotics.


DENARASE® is a registered trademark of c-LEcta GmbH in the European Union (EU), United States of America (USA), China (CN), India (IN), South-Korea (KR) and Japan (JP).


Product Article Number Size Purity Activity Price
DENARASE, 1 MU  20804-1M 1 MU 
(1.000.000 Units)
≥ 99% > 250 U/µl on request
DENARASE, 5 MU 20804-5M 5 MU 
(5.000.000 Units)
≥ 99% > 250 U/µl on request
DENARASE, 100 kU  20804-100k 100 kU 
(100.000 Units)
≥ 99% > 250 U/µl 325,00 €

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DENARASE, 500 kU 20804-500k 500 kU 
(500.000 Units)
≥ 99% > 250 U/µl 990,00 €

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The products DENARASE, 1 MU and DENARASE, 5 MU (Article Number: 20804-1M, 20804-5M) are for routine applications (produced and filled under GMP).

The products DENARASE, 100 kU and DENARASE, 500 kU (Article Number: 20804-100k, 20804-500k) can be used for laboratory test applications (produced under GMP and filled under ISO 9001).

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